Chromosomal Alterations: Origin and Significance
D. Schulte-Frohlinde (auth.), Professor Dr. Günter Obe, Professor Dr. Adayapalam T. Natarajan (eds.)Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered.
Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.
Categorias:
Ano:
1994
Edição:
1
Editora:
Springer-Verlag Berlin Heidelberg
Idioma:
english
Páginas:
402
ISBN 10:
3642788890
ISBN 13:
9783642788895
Arquivo:
PDF, 11.42 MB
IPFS:
,
english, 1994
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